Quinoxaline as a potent heterocyclic moiety
نویسندگان
چکیده
منابع مشابه
The Benzyl Moiety in a Quinoxaline-Based Scaffold Acts as a DNA Intercalation Switch.
Quinoxaline antibiotics intercalate dsDNA and exhibit antitumor properties. However, they are difficult to synthesize and their structural complexity impedes a clear mechanistic understanding of DNA binding. Therefore design and synthesis of minimal-intercalators, using only part of the antibiotic scaffold so as to retain the key DNA-binding property, is extremely important. Reported is a uniqu...
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ژورنال
عنوان ژورنال: IOSR Journal of Pharmacy (IOSRPHR)
سال: 2014
ISSN: 2319-4219,2250-3013
DOI: 10.9790/3013-040120101617027